Protein Molecular Weight Markers
Cayman Chemical PI-103hydrochlorIde 10mg
A selective FLT3 inhibitor (Kd 1 6 nM) that inhibits the proliferation of MV4-11 cells both in vitro (IC50 0 56 nM) and in in vivo mouse models of FLT3-ITD acute myeloid leukemia
R Peptide LLC Tau Protein Ladder, of all 6 isoforms, 50 uL
Tau is a family of major neuronal microtubule associated proteins that are found in the neurofibrillary tangles (NFT) in Alzheimer's disease. Tau promotes the assembly and maintains the structure of microtubules in neuronal cells. The Tau proteins are derived from alternative mRNA splice variants that originate from a single gene and result in mature proteins that vary in size from 352 to 441 amino acids (36.8 to 45.9 kDa).
Fisher BioReagents™ EZ-Run™ Protein Marker
Mixture of seven purified proteins optimized to produce uniform, compact bands when analyzed by SDS-PAGE and stained with Coomassie™ Blue
Fisher BioReagents™ EZ-Run™ Prestained Protein Marker
Ideal for monitoring protein separation during electrophoresis without staining and for verifying electroblotting of proteins onto membranes
Fisher BioReagents™ EZ-Run™ Rec Protein Ladder
Mixture of 14 highly purified recombinant proteins optimized for precise sizing of proteins by SDS-PAGE and Western blotting
Cayman Chemical Carbmylatd Alph1 ntItryp 500uL
An inhibitor of ATG4B inhibits ATG4B cleavage of LC3B-GST (IC50 51 UM) and reduces LC3B lipidation induced by starvation in Saos-2 cells reduces starvation-induced autophagy and prevents autophagic vacuole formation in Saos-2 and MDA-MB-468 cells (100 UM) decreases autophagy in vivo in mouse liver inhibits tumor growth in mouse xenograft model and decreases the number of autophagic vacuoles in osteosarcoma tumors (100 mg/kg)
Cayman Chemical p62SQSTM1 PolYCNl ntIbod 500uL
A B2-AR agonist selectively binds to B1- over B2-ARs (Kds 2.9 and 113 nM respectively) as well as B3-adrenergic B2 bradykinin NK1 and NK2 receptors up to 3 M induces cAMP accumulation in cultured human bronchial epithelial cells relaxes guinea pig tracheal strips precontracted with carbamoylcholine ovalbumin or histamine (pD2s 8.4 9.5 and 9.5 respectively) reverses histamine- and ovalbumin-induced bronchoconstriction in guinea pigs (ED50s 1 and 40 nmol/kg respectively)